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Company : Mulei (Wuhan) New Material Technology Co. Ltd
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Product name : Pregabalin
Pregabalin CAS : 148553-50-8 ,
Pregabalin 25mg MF:C8H17NO2
Pregabalin 25mg MW:159.23
Pregabalin 25mg EINECS:604-639-1
Pregabalin 25mg Melting point:194-196°C
Pregabalin 25mg alpha D23 +10.52° (c = 1.06 in water)
Pregabalin 25mg Boiling point:274.0±23.0 °C(Predicted)
Pregabalin 25mg Density 0.997±0.06 g/cm3(Predicted)
Pregabalin 25mg Flash point : 9℃
Pregabalin 25mg storage temp. Store at RT
Pregabalin 25mg solubility deionized water: ≥10mg/mL
Pregabalin 25mg Pka : 4.23±0.10(Predicted)
Pregabalin 25mg Form : white powder
Pregabalin was approved for medical use in the United States in 2004. Pregabalin was developed as a successor to gabapentin. Pregabalin is available as a generic medication in a number of countries, including the United States as of 2019. In 2018, Pregabalin was the 70th most commonly prescribed medication in the United States, with more than 11 million prescriptions. In the US, pregabalin is a Schedule V controlled substance under the Controlled Substances Act of 1970. Pregabalin is a Class C controlled substance in the UK .
Pregabalin can decrease sperm count and may affect fertility in men (your ability to have children). In animal studies, pregabalin also caused birth defects in the offspring of males treated with this medicine. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk. You should not breastfeed while using pregabalin.
Pregabalin is an inhibitor of neuronal activity used for therapy of painful neuropathy and as an anticonvulsant. Therapy with pregabalin is not associated with serum aminotransferase elevations, and clinically apparent liver injury from pregabalin has been reported but appears to be quite rare.
Pregabalin is useful when added to other treatments, when those other treatments are not controlling partial epilepsy. Pregabalin use alone is less effective than some other seizure medications. Pregabalin is unclear how it compares to gabapentin for this use .
Pregabalin is generally not regarded as efficacious in the treatment of acute pain. In trials examining the utility of pregabalin for the treatment of acute post-surgical pain, no effect on overall pain levels was observed, but people did require less morphine and had fewer opioid-related side effects. Several possible mechanisms for pain improvement have been discussed .